Can Modafinil Get You High?

Written on February 17, 2022 by | Reviewed by William Gallagher, MNeuroSci

The short answer is No! Mod

The long answer is more interesting. Modafinil, also known as Provigil, adds in a very unique and interesting way to the arsenal of available nootropics, or smart drugs.

Let's look at the science behind why it is unlikely that you will "get high" on modafinil.

Why It Could Make You High

Modafinil works by altering the levels of wakefulness-promoting neurotransmitters in the brain like dopamine and norepinephrine.

It may also alter other neurotransmitters such as histamine, glutamate and GABA - which are responsible for regulating things like mood.

People who are taking modafinil report feelings of intense mental clarity, increased energy levels, euphoria, enhanced focus and concentration.

Many even report mild hallucinogenic effects and "high" with extreme cases involving derealization (taking on a dissociative state) along with an increase in feelings of euphoria.

The Modafinil High

So, what's behind the modafinil high?

Well, it seems that the primary drivers of the high are dopamine and norepinephrine.

Dopamine is associated with feelings of pleasure while norepinephrine is responsible for the "fight or flight" response.

Together, they can create a strong sense of euphoria, excitement and energy.

Modafinil also seems to increase levels of histamine in some people. Histamine is linked with feelings of arousal and is partly responsible for the "high" that people feel when they take drugs like amphetamines.

So, it's clear that there are some strong drivers behind the modafinil high.

But why is it that only some people experience these effects?

Well, it seems that it has to do with the way that modafinil interacts with your individual brain chemistry.

Some people have a higher sensitivity to the effects of dopamine and norepinephrine than others and this is what leads to the stronger "high" response.

What To Look Out For

It's important to note that people who experience a high from modafinil should be careful as it can be addictive.

People who are predisposed to addiction or have a history of drug abuse are more likely to become addicted to modafinil.

It's also important to note that there is a risk of developing psychiatric side effects, such as mania, psychosis and aggression, while taking modafinil.

So, if you're thinking of taking modafinil, it's important to be aware of the risks and to speak to your doctor before starting.

Like any other drug you also run into the risk of developing a tolerance to it which will require you to take more and more of the drug to achieve the same effects.

So, Can Modafinil Get You High?

The short answer is no. The long answer is that it depends on your individual brain chemistry and the dose you take.

Modafinil interacts with dopamine and norepinephrine to produce feelings of euphoria and excitement in some people.

People who are predisposed to addiction or have a history of drug abuse are more likely to become addicted to modafinil.

There is also a risk of developing psychiatric side effects while taking modafinil which should be considered before starting. Tolerance to the drug can also develop over time.

So, while modafinil may not produce a traditional "high" in everyone, it does have the potential to create strong feelings of pleasure and excitement in some people.

So, if you're thinking of taking modafinil, it's important to be aware of the risks and speak to your doctor first.