What is Alpha GPC good for?

What is Alpha GPC good for?

In this article I’ll take a closer look at the popular Nootropic called; Alpha-GPC. I’ll cover what it is exactly, who can include it in their nootropic stack and the benefits that it has to offer. So what is Alpha GPC good for?

Alpha-GPC is a nootropic that works to support cognitive functions such as memory and learning. It can be taken on its own or in combination with other nootropics in a stack.

This supplement is great for anyone looking to improve their cognition and mental ability while reducing the potential effects of ageing on the brain. It has been shown to help reduce anxiety, improve focus and memory and even stimulate brain cell growth.



Benefits of Alpha GPC

  • Memory improvement
  • Focus and attention
  • Reduction in stress
  • Reduced age related cognitive decline

This supplement is able to provide you with a number of benefits, however the way it works to help you achieve them is slightly different to other brain supplements.

Unlike many nootropics which work directly on supporting brain function, Alpha-GPC works indirectly by supporting acetylcholine (ACh) levels in the brain.

Acetylcholine is a neurotransmitter that is responsible for communication between neurons.

This is important because the more acetylcholine in your system the better your overall cognitive abilities will be. It also helps support your nervous system and general health.

The way it helps you achieve this is by helping your brain produce more acetylcholine. The supplement does this by converting into acetylcholine within your brain cells.

Alpha-GPC works in a similar way to when you take choline supplements, which are also used to maximise ACh levels in the brain.

I find that choline supplements can be a bit hit and miss for some people, as they aren’t able to increase ACh levels in some people’s brains. This can also happen with Alpha-GPC although its effects are generally more reliable than those of choline supplements.

That being said, most nootropics (including Alpha-GPC) have been shown to have side effects if taken too much or in combination with other supplements.


Dosage & Side Effects of Alpha GPC

One of the main side effects of nootropics is insomnia, which is a very common. This can be incredibly frustrating and you could end up going through periods where you feel like you’ll never sleep again. I’ve been there.

Alpha-GPC is also known to cause headaches, nausea and stomach issues. In terms of dosage you should stick to around 600mg per day, as this is all the body can usually handle.

Although Alpha-GPC can be taken on its own it can also be taken in combination with other supplements to make the effects more intense.

As a nootropic, it is impossible for me to say whether or not this supplement is right for you.

The dosage is just one of the things that I think about when considering taking this supplement, but if you’re in doubt I’d suggest speaking to your doctor first.


CDP-Choline vs. Alpha-GPC

Although CDP-Choline is used as a choline source, it isn’t recommended that you take it in conjunction with Alpha-GPC as you may experience side effects.

CDP-Choline is made of two molecules of citicoline combined with one molecule of Choline and is known for its smoother cognitive effects compared to Alpha-GPC. However; since

CDP-Choline is not associated with any side effects, it can be taken on its own or in combination with other nootropics, such as Alpha-GPC.

Alpha-GPC is made of one molecule of Choline and Glycerol and is known for its more effective cognitive effects compared to CDP-Choline.

That being said, both have the aim to increase acetylcholine levels within the brain. They also work at slightly different rates, with Alpha-GPC being able to convert into acetylcholine quicker than citicoline.

Both are great supplements for improving cognitive capabilities in the long run but you should be aware that if you combine them you may experience headaches and gastrointestinal issues.

However; while researching this article I came across a study that showed a significant difference in the result of CDP-Choline vs. Alpha-GPC when it was taken in the same amounts.

This interesting finding suggests that there is in fact a difference between the two, however both are effective at increasing ACh levels.

I find this surprising as it was found that Alpha-GPC was better at increasing acetylcholine levels than CDP Choline. Alpha-GPC had much greater effect on ACh levels than CDP-Choline, however; they both worked in similar amounts.


Where Can I Buy Alpha GPC?

Alpha-GPC has become very popular over the last few years and is now available from most online retailers. This supplement can also be bought from many local supplement shops and health stores.

Alpha-GPC is relatively inexpensive compared to many other nootropics.

You’ll most likely end up paying around $15 for 60 150mg capsules – although you should always check the recommended daily dosage on the supplement before you decide whether to take it or not.



Alpha-GPC is a supplement that has been used for years by over the counter formulators and is often found in cheap choline based products.

It is usually just made of one molecule of Choline and Glycerol but it still does a great job at increasing both acetylcholine levels and ACh synthesis.

Where the main side effects come from are the headaches, nausea and stomach issues, which can be annoying if you’re taking Alpha-GPC as part of your nootropic stack.

When compared to CDP-Choline, Alpha-GPC is more effective at increasing ACh levels and is a lot less likely to cause side effects.

Overall, I think that both Alpha-GPC and CDP Choline have a place in a nootropic stack and should be taken alongside other supplements to enhance the effects.

It’s been found that if you combine them the effects are much stronger but this doesn’t mean to say that it’s not possible to take Alpha GPC on its own.


Where can I read more about Alpha-GPC?

I recommend sticking to websites that are reputable, have a good reputation and maybe even those that post in-depth reviews of various supplements.

If you have any questions why you should take Alpha GPC as opposed to other Nootropics (or you want to share your experiences with it) then please leave a comment below. I always love hearing from my readers and will get back to you as soon as possible! 🙂

And if you enjoyed this article why not share it on Facebook, Twitter or Reddit? It’d be greatly appreciated! I’ve also put together a few more articles that might interest you down below.

– Peace!


  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629791/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691701/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683073/
  4. https://www.nature.com/articles/srep13188
  5. https://examine.com/supplements/alpha-gpc/

Go Back to homepage


Recent Posts

error: Content is protected !!