Noopept vs. Pramiracetam - What's The Difference?

Updated November 6, 2024 by | Reviewed by William Gallagher, MNeuroSci
(Estimated reading time: 3 minutes)

In this article, I want to compare and contrast two nootropics: Noopept and Pramiracetam. I will discuss what they do, the benefits/drawbacks of each, and the current prices. I will also look at some of their similarities and differences.

So without further ado, let's just get straight into it, shall we?

Noopept Compared to Pramiracetam

Noopept (or GVS-111) is a cognitive-enhancing Smart drug that was initially developed in Russia. It is structurally derived from the racetam family of drugs, but it is much more potent than its predecessors.

Noopept has a short half-life of around (15 minutes in rodents), meaning that its effects wear off quickly. Typically, Noopept will be taken 1-2 times per day at a dosage of 10-30mg.

Pramiracetam, on the other hand, is another highly potent nootropic. It is also a racetam family of drug and was developed by Parke-Davis in the late 70s, making it one of the older and better-known nootropics.

Pramiracetam works by increasing glutamate transmission and cholinergic activity in the brain.

This leads to improved cognition via enhanced communication between different parts of the brain. This drug has been shown to improve learning and memory, as well as increase the ability to pay attention.

Pramiracetam is generally taken 1-2 times per day at a dosage of 100-200mg.

Noopept Drawbacks

The main drawback of Noopept is that it wears off within 30 minutes. This means that taken once or twice a day, it would not be effective for an extended period of time. Typically, this drug is taken before an exam or stressful event (e.g. an interview).

The benefits of Noopept are its high potency and ability to improve short-term memory formation.

This is also one of the most powerful nootropics that is available on the market today, in terms of its ability to increase cognition and mental function in general.

Pramiracetam Drawbacks

Pramiracetam is a potent nootropic, but it is slightly different than Noopept in terms of its effects. It will still help to increase cognition, memory function, and learning, but it has more of an effect at improving attention and focus.

This means that it may be slightly better for students who have to concentrate on particular subjects rather than all-around brain function.

Pramiracetam also has a longer half-life of 6 hours. This means that it will possess effects even after an extended period of time, which is great for those who take multiple doses throughout the day.

Which One is Better?

As you can see, there are a number of similarities between these two nootropics. Both have been shown to work effectively and both have a similar price-tag to that of Piracetam.

This means that if you are looking for something that will improve your overall cognition, Noopept may be your best choice. However, if you are looking for something that will boost your memory and focus, then Pramiracetam may be the better option.

The ultimate decision as to which one is better ultimately comes down to your own needs and expectations. Don't worry about choosing the wrong one, either - as they both work effectively and both are relatively safe for long-term consumption.

The prices of both of these nootropics are very similar. You can currently purchase Pramiracetam powder at $11.99 for 5 grams, while Noopept can be purchased for anywhere from $20 to $50.

It's ideal to take these nootropics on a regular basis, but in the case of sudden stressful situations or important exams, taking some Noopept beforehand may be advantageous.

This way you will have some cognitive edge over other people and improve your chances of success.