11 Best Nootropics For Happiness in 2024

Updated March 9, 2024 by | Reviewed by William Gallagher, MNeuroSci
(Estimated reading time: 12 minutes)

In this article, I'll be reviewing 11 nootropics that will help make you happier overall.

These nootropics are non-habit forming and generally safe to consume.

You may already be familiar with some or many of these nootropics - however, it helps to have a comprehensive list of suggestions so that you know what to avoid.

I'll be listing the pros and cons of each nootropic.

The 11 best nootropics for happiness according to scientific evidence are:

  1. Vyvamind
  2. N-Acetyl Cysteine
  3. L-tyrosine
  4. Phenibut
  5. Rhodiola Rosea
  6. Ashwagandha
  7. Ginkgo Biloba
  8. Vinpocetine
  9. SAMe (S-Adenosyl-L-Methionine)
  10. Uridine
  11. L-theanine

1. Vyvamind

Vyvamind contains 6 all-natural, clinically-proven ingredients that have been shown to improve mood, memory, focus, and energy.

The 6 ingredients are:

  1. Vitamin B6
  2. Vitamin B12
  3. L-Tyrosine
  4. CDP-Choline
  5. L-Theanine
  6. Caffeine Anhydrous

Vyvamind can give you unparalleled focus and clarity, increase motivation and drive, and help improve your mood and cognitive function.

The great thing about Vyvamind is that it's a nootropic blend meaning that the different ingredients work together synergistically to produce an effect that is greater than the sum of its parts.

That way you also avoid having to buy and take each ingredient separately which can be costly and inconvenient.

Vyvamind Pros

  • 6 clinically-proven ingredients
  • Improves mood, memory, focus, and energy
  • Non-GMO and allergen-free

Vyvamind Cons

  • You have to take it regularly for benefits to accumulate
  • May cause headaches and jitters in some people

Vyvamind in Summary

Vyvamind is a great mood booster and cognitive enhancer that can help you feel happier overall.

It's new on the market but the ingredients have all been clinically proven to be effective.

Just be aware that it may cause some side effects like headaches and jitters in some people and that you need to take it regularly for the benefits to accumulate.

2. N-Acetyl Cysteine

N-Acetyl Cysteine is a neurochemical that helps to protect the brain from damage.

It is also an antioxidant, which means it helps to reduce free radicals and inflammation.

N-Acetyl Cysteine also helps to increase levels of glutathione, a key neurotransmitter involved in regulating mood and stress.

In addition, N-Acetyl Cysteine has been shown to boost levels of BDNF, a protein that helps to support nerve growth and regeneration.

As a result, N-Acetyl Cysteine has powerful neuroprotective and mood-enhancing effects.

Therefore, it is not surprising that N-Acetyl Cysteine has been shown to be an effective nootropic for happiness.

N-Acetyl Cysteine Pros

  • Protects the brain from damage
  • Reduces free radicals and inflammation
  • Increases levels of glutathione
  • Boosts levels of BDNF
  • Has mood-enhancing effects

N-Acetyl Cysteine Cons

  • May cause gastrointestinal upset in some people
  • May interact with certain medications

N-Acetyl Cysteine in Summary

N-Acetyl Cysteine is a potent nootropic with neuroprotective and mood-enhancing effects.

It is generally well-tolerated but may cause gastrointestinal upset in some people.

N-Acetyl Cysteine is a great option for people looking for a nootropic to improve their mood and happiness without having to worry about side effects.

3. L-tyrosine

Tyrosine is a common amino acid that is found in many foods.

It plays an important role in the production of dopamine and norepinephrine, two neurotransmitters that are associated with mood and focus.

Tyrosine levels are known to drop during times of stress, so supplementation can help to support cognitive function during these times.

L-tyrosine is a more bioavailable form of tyrosine and has been shown to be more effective at raising dopamine and norepinephrine levels.

This increases feelings of pleasure and well-being, which can lead to improved mood and focus.

In addition, L-tyrosine has been shown to improve symptoms of depression and anxiety.

Overall, L-tyrosine is a safe and effective nootropic that can help to support cognitive function and happiness.

L-tyrosine Pros

  • Supports cognitive function during times of stress
  • Raises dopamine and norepinephrine levels
  • Improves mood and focus
  • Safe and effective

L-tyrosine Cons

  • May cause gastrointestinal upset in some people
  • May interact with certain medications

L-tyrosine in Summary

L-tyrosine is a safe and effective nootropic that can help to support cognitive function and happiness.

It is generally well-tolerated but may cause gastrointestinal upset in some people.

L-tyrosine is a great option for people looking for a nootropic to improve their mood, happiness and focus.

4. Phenibut

Phenibut is a Nootropic supplement that has been shown to be effective in reducing anxiety and improving mood.

Phenibut works by affecting the levels of GABA, a neurotransmitter that is responsible for regulating the level of anxiety and stress in the brain.

Phenibut also affects the levels of dopamine and serotonin, two other neurotransmitters that are responsible for regulating mood.

By increasing the levels of these neurotransmitters, Phenibut can help to improve mood and reduce anxiety.

Phenibut is available over-the-counter and does not require a prescription.

It is important to note that Phenibut can cause side effects when taken in large doses or when used for extended periods of time.

When used as directed, however, Phenibut is a safe and effective way to improve mood and reduce anxiety.

Phenibut Pros

  • Reduces anxiety
  • Improves mood
  • Safe and effective
  • Available without a prescription

Phenibut Cons

  • Can cause serious withdrawal symptoms
  • May interact with certain medications

Phenibut in Summary

Phenibut is a safe and effective way to reduce anxiety and improve mood.

It is available without a prescription and is generally well-tolerated.

Phenibut is a great option for people looking for a nootropic to improve their mood and reduce anxiety.

5. Rhodiola Rosea

Rhodiola Rosea, also known as golden root or arctic root, is a perennial flowering plant in the cabbage family.

It grows in cold, mountainous regions of Europe, Asia, and North America.

Historically, Rhodiola Rosea has been used as herbal medicine to treat a variety of conditions, including fatigue, anxiety, and depression.

Today, it is commonly taken as a dietary supplement to promote mental and physical health.

Rhodiola Rosea is thought to work as a nootropic due to its purported effects on the nervous system.

Specifically, Rhodiola Rosea is said to increase levels of serotonin and dopamine in the brain, two neurotransmitters that are essential for happiness and wellbeing.

Additionally, Rhodiola Rosea is believed to reduce stress levels by modulating the body's stress response.

While more research is needed to confirm these claims, preliminary evidence suggests that Rhodiola Rosea may be an effective natural treatment for anxiety and depression.

Rhodiola Rosea Pros

  • Historically used to treat anxiety and depression
  • May increase levels of serotonin and dopamine
  • May reduce stress levels

Rhodiola Rosea Cons

  • May cause gastrointestinal upset in some people
  • May interact with certain medications

Rhodiola Rosea in Summary

Rhodiola Rosea is a perennial flowering plant that has been historically used to treat anxiety and depression.

Today, it is commonly taken as a dietary supplement to promote mental and physical health.

Rhodiola Rosea is thought to work as a nootropic due to its purported effects on the nervous system.

While more research is needed to confirm these claims, preliminary evidence suggests that Rhodiola Rosea may be an effective natural treatment for anxiety and depression.

6. Ashwagandha

Ashwagandha is an ancient Indian medicinal herb that has been used for centuries to treat a variety of conditions.

Recently, it has gained popularity as a nootropic, or cognitive enhancer, due to its ability to improve memory and reduce stress.

The active compounds in ashwagandha, including withanolides and alkaloids, are thought to exert their benefits by modulating the activity of neurotransmitters such as dopamine and serotonin.

Additionally, ashwagandha has been shown to increase levels of brain-derived neurotrophic factor (BDNF), a protein involved in neuronal growth and plasticity.

By improving neurotransmitter function and increasing BDNF levels, ashwagandha may help to improve mood, memory, and cognitive function.

In addition to its nootropic effects, ashwagandha is also known for its ability to reduce stress and anxiety.

This may be due to its adaptogenic properties, which help the body to better cope with physical and psychological stressors.

For these reasons, ashwagandha is often referred to as the “herbal Prozac”.

If you’re looking for a natural way to boost your mood and cognitive function, ashwagandha may be worth trying.

Ashwagandha Pros

  • Improves memory
  • Increases levels of brain-derived neurotrophic factor
  • Adaptogenic properties help the body to better cope with stress
  • Improves mood and cognitive function
  • Reduces anxiety

Ashwagandha Cons

  • Can cause GI upset in some people
  • May interact with certain medications
  • Large dosages may be necessary to see benefits

Ashwagandha in Summary

If you're looking for a natural way to boost your mood and cognitive function, ashwagandha may be worth trying.

It has been used traditionally in India for centuries and has only recently gained popularity as a nootropic.

The active compounds in ashwagandha help to improve neurotransmitter function and increase levels of brain-derived neurotrophic factor which helps to improve mood, memory, and cognitive function.

7. Ginkgo Biloba

Ginkgo biloba is a tree that is native to China.

The leaves of the tree are often used in traditional Chinese medicine.

The leaves of the tree are used to make an extract, which is thought to have a variety of health benefits.

One of these potential benefits is its role as a nootropic.

Nootropics are substances that are thought to improve cognitive function.

Some evidence suggests that Ginkgo Biloba may help to improve memory, mood and attention span.

Additionally, Ginkgo Biloba is sometimes used as a natural treatment for depression.

Ginkgo Biloba is also sometimes used as a natural treatment for anxiety.

Ginkgo Biloba Pros

  • Helps improve memory
  • Helps improve mood
  • Helps improve attention span

Ginkgo Biloba Cons

  • Gingko can thin your blood, so it interacts with many medications
  • It can cause some side effects like nausea, diarrhea, and headaches

Ginkgo Biloba in Summary

Ginkgo biloba is a great natural choice if you're looking for a nootropic to help improve your cognitive function.

It has been used in traditional Chinese medicine for centuries so its safety profile is well-known.

When used as a mood booster, it can help improve your memory, attention span, happiness and energy levels.

8. Vinpocetine

Vinpocetine is a nootropic supplement that has gained popularity in recent years as a means of improving cognitive function.

Vinpocetine is derived from the Periwinkle plant and has been used in traditional medicine for centuries.

Modern science has shown that Vinpocetine can help to improve blood flow to the brain, increase cognitive function, and protect against age-related cognitive decline.

Vinpocetine is thought to work as a Nootropic by helping to increase levels of the neurotransmitter acetylcholine.

Acetylcholine is involved in many different cognitive processes, including memory and learning. By increasing levels of acetylcholine, Vinpocetine may help to improve cognitive function.

Additionally, Vinpocetine is known to have antioxidant properties, which may protect the brain from damage caused by free radicals.

Overall, Vinpocetine is a safe and effective supplement that can help to improve cognitive function and protect the brain from age-related decline.

Vinpocetine Pros

  • Improves cognitive function
  • Increases blood flow to the brain
  • Protects against age-related cognitive decline
  • Increases levels of the neurotransmitter acetylcholine
  • Involved in many different cognitive processes

Vinpocetine Cons

  • Flushing of the face
  • May cause some side effects like headaches and dizziness

Vinpocetine in Summary

Vinpocetine is a powerful cognitive enhancer that has been shown to improve brain function, protect against age-related cognitive decline, and increase levels of the neurotransmitter acetylcholine.

It is involved in many different cognitive processes, making it an important supplement for anyone looking to improve their mental performance.

9. SAMe (S-Adenosyl-L-Methionine)

SAMe is a naturally occurring chemical in the human body that plays an important role in many biochemical processes.

It is produced largely by the liver and is also found in small amounts in other tissues such as the brain and kidneys.

SAMe has gained popularity as a dietary supplement due to its purported benefits for mental health, including depression and anxiety.

A number of clinical studies have shown that SAMe is effective for treating depression, and it is thought to work by increasing levels of serotonin and other neurotransmitters in the brain.

SAMe is also commonly used as a supplement for joint health, as it helps to protect cartilage and reduce inflammation.

In addition, SAMe has shown promise as a treatment for liver diseases such as hepatitis and cirrhosis.

While SAMe is generally safe and well-tolerated, it can cause side effects such as nausea, headache, and anxiety.

Therefore, it is important to speak with a healthcare provider before taking SAMe or any other dietary supplement.

SAMe (S-Adenosyl-L-Methionine) Pros

  • Successfully treats depression
  • Boosts serotonin levels
  • Prevents cartilage degradation and joint pain
  • Alleviates liver diseases such as hepatitis and cirrhosis
  • Safe and well tolerated

SAMe (S-Adenosyl-L-Methionine) Cons

  • Can cause digestive problems
  • Can cause mild insomnia
  • Dizziness
  • Irritability
  • Anxiety
  • Sweating

SAMe (S-Adenosyl-L-Methionine) in Summary

Overall, SAMe appears to be a very safe and well-tolerated supplement with a wide range of potential health and mood benefits.

While it may cause some minor side effects like digestive problems, insomnia, or dizziness in some people, these are usually mild and go away over time.

Additionally, there have been no major safety concerns reported with SAMe use.

If you are considering taking this supplement, make sure to speak with your doctor first to find out if it is the right choice for you.

10. Uridine

Uridine is a nucleotide found in RNA.

It is also found in foods like beer and tomatoes.

Uridine supplementation increases levels of dopamine and other feel-good neurotransmitters in the brain.

This leads to improved mood, increased motivation, and reduced stress.

Uridine also helps to protect the brain from age-related damage and improves cognitive function.

In addition, uridine has been shown to reduce anxiety and improve sleep quality.

Overall, uridine is an effective nootropic for happiness. It works by increasing levels of dopamine and other happy neurotransmitters in the brain.

This leads to improved mood, increased motivation, and reduced stress. Uridine also helps to protect the brain from age-related damage and improves cognitive function.

As a result, it is an excellent supplement for those looking to boost their mood and improve their overall well-being.

Uridine Pros

  • Aids in the production of dopamine
  • Improves mood
  • Reduces stress
  • Protects the brain from age-related damage
  • Increases cognitive function

Uridine Cons

  • May cause digestive upset
  • Can interact with some medications
  • May cause headaches in some people

Uridine in Summary

Uridine is an effective nootropic for happiness. It works by increasing levels of dopamine and other happy neurotransmitters in the brain.

Uridine is an essential compound that helps the body and brain work more efficiently. It also protects against age-related damage, improves cognitive function in old age (and even helps you learn new things!), while increasing motivation levels!

Because of this, it's a wonderful mood enhancer and general wellness booster for people seeking to improve their emotional well-being.

11. L-theanine

L-theanine is an amino acid commonly found in green tea.

It is also available as a supplement, and many people take it for its purported health benefits.

L-theanine is thought to promote relaxation and reduce stress, anxiety, and impulsivity.

It works by increasing levels of GABA, serotonin, and dopamine in the brain.

These neurotransmitters are responsible for regulating mood, sleep, and energy levels.

Some research suggests it may also improve cognitive function and attention span.

As a result, L-theanine is sometimes referred to as a "nootropic" or "smart drug."

While more research is needed to determine the full extent of its effects, L-theanine seems to be safe for most people when taken in moderate doses.

If you're looking for a natural way to boost your mood and mental well-being, L-theanine may be worth trying.

L-theanine Pros

  • A natural way to boost mood
  • May help reduce stress and anxiety
  • May improve cognitive function
  • Safe for most people

L-theanine Cons

  • May cause drowsiness in some people
  • May cause digestive upset in some people

L-theanine in Summary

L-theanine is an amino acid found in green tea, and it has a variety of potential health benefits.

It is thought to promote relaxation and reduce stress, anxiety, and impulsivity, and it works by increasing levels of GABA, serotonin, and dopamine in the brain.

These neurotransmitters are responsible for regulating mood, sleep, and energy levels.

What Are the Best Nootropics for Happiness?

While the term "nootropic" is often used to refer to substances that improve cognitive function, there is no strict definition of what qualifies as a nootropic.

As such, there are many different substances that could potentially be classified as nootropics, and their effects can vary widely.

Some nootropics may have mood-boosting properties, while others may help to reduce stress or promote relaxation.

Therefore, when trying to determine which nootropic is best for happiness, it is important to consider what your specific goals are.

If you are looking for a nootropic that will help to boost your mood, then something like Phenibut may be a good option.

If you are looking for something that will help you to relax and reduce stress, then herbs like L-theanine and/or Ashwagandha may be a better choice.

You can also find nootropic blends like Vyvamind which contains a variety of different ingredients, which may be a good option if you are looking for a well-rounded product.

Ultimately, the best nootropic for happiness is the one that works best for you and meets your specific needs.

What Are the Benefits of Nootropics for Happiness?

When it comes to happiness, nootropics can offer a variety of potential benefits.

Some nootropics may help to improve mood by increasing levels of happy neurotransmitters like dopamine and serotonin.

Others may help to reduce stress or promote relaxation.

Still, others may improve cognitive function and attention span, which can indirectly lead to increased happiness.

In my personal experience, I have found that a combination of different nootropics works best for happiness:

I like to take Phenibut or L-theanine when I am feeling stressed or anxious, and I take Vyvamind when I need a mood and/or cognitive boost.

I find that this approach helps me to feel my best and happiest.

So to give an overview of the most beneficial aspects of nootropics:

  • They help to improve mood by increasing levels of happy neurotransmitters like dopamine and serotonin
  • They help to reduce stress or promote relaxation
  • They improve cognitive function and attention span, which can indirectly lead to increased happiness
  • They are a great way to naturally improve your mood and mental well-being

If you are looking for a natural way to boost your mood, then nootropics may be worth considering.

Just make sure to do your research and choose a product that is right for you.

What Are the Side Effects of Nootropics for Happiness?

Nootropics are a class of psychoactive substances that are becoming increasingly popular as a means of enhancing mental performance and mood.

While many nootropics are considered to be safe and effective, there is some concern about the potential side effects of these drugs, particularly when used in higher doses.

The most common side effect of nootropics is insomnia, which can be caused by the stimulating effects of some of these drugs.

Other potential side effects include:

  • Anxiety
  • Irritability
  • Headaches

In rare cases, more serious side effects such as mania and psychosis have been reported.

Overall, however, the vast majority of people who use nootropics do not experience any negative side effects.

When taken at moderate doses, these substances can safely improve mental performance and mood without causing any significant adverse effects.

Final Thoughts: Do Nootropics Really Work for Happiness?

In my personal opinion, yes, nootropics can definitely work for happiness.

I have personally used a variety of different nootropics, and I can attest to their mood-boosting and stress-reducing effects.

If you are looking for a natural way to improve your mood, cognitive function, and overall well-being, then nootropics may be worth considering.

If you're looking for a nootropic blend that can help boost your mood the natural way, I highly recommend taking a closer look at Vyvamind right here: