N-Acetyl Selank Amidate: A Nootropic that boosts Mood & Memory

Updated May 13, 2024 by | Reviewed by William Gallagher, MNeuroSci
(Estimated reading time: 4 minutes)

For years, Russians have been using a nootropic called Selank to boost mood and memory. It was originally created for epileptic patients with severe depression who had trouble remembering things.

However, a new analog of the drug has become very popular among Russian students called; N-acetyl Selank amidate.

The drug is not approved in the United States or Canada, but that doesn't mean you can't get your hands on it!

In this article, we'll analyze how this wonder drug works and what results you can expect.

We'll also discuss the legality of N-acetyl Selank amidate in North America as well as its potential side effects.

First things first, what is N-Acetyl Selank amidate?

The newest analog of Selank is N-acetyl Selank amidate, which has a greater crossing ability across the blood-brain barrier than does Selank.

N-acetyl Selank is more potent and has increased bioavailability and stability.

In other words, the drug has a greater ability to enter the brain and work its magic!

It has also been shown to regulate the expression of interleukin-6 (IL-6), neurotransmitter monoamine concentration, and serotonin production.

One of the main reasons why N-acetyl Selank has grown so popular in recent years is its capacity to regulate the body's stress response (particularly coping mechanisms.)

It has been authorized in Russia for the treatment of generalized anxiety disorder (GAD) and as a nootropic.

According to studies, selank has been linked to higher levels of BDNF, a critical brain-growth protein (neurotrophic factor) that has been linked to learning and memory.

The researchers proposed that this mechanism may be responsible for some of selank's cognitive benefits.

Selank has also been found to reduce anxiety symptoms, enhance learning capacity, stabilize memory traces, promote brain activity, and alleviate depression symptoms in animal and human studies.

What Are the Potential Benefits of N-Acetyl Selank?


As briefly mentioned above, N-acetyl Selank helps regulate the body's stress response, which is critical for improving mood and memory.

It also reduces anxiety levels by balancing neurotransmitters in your brain (like GABA).

N-acetyl Selank has been shown to increase BDNF, a protein that promotes neurogenesis or new cell growth in the hippocampus part of the brain.

Nootropics like N-acetyl Selank also promote neuroplasticity or the ability of your brain to form new connections between neurons (synapses).

This is one reason why it has strong effects on memory and learning capacity.

What Are The Potential Side Effects?

N-acetyl Selank is considered very safe for most people.

That being said, the most common side effects include:

A slight headache, which is pretty normal for any nootropic or supplement that increases blood flow to your brain.

It's a temporary effect and should go away after a few hours.

Drowsiness. Again, this only lasts a couple of hours as well! You can avoid these two negative side effects by taking the supplement with a choline source (like Alpha-GPC).

How Is N-acetyl Selank Different from Semax?

Semax and N-Acetyl Selank are both synthetic peptides that may provide cognitive benefits.

However, Semax is a brain hormone that has various applications, such as preventing liver damage and promoting blood circulation.

N-acetyl Selank is a more effective and bioavailable version of Selank, which is an anxiolytic peptide that reduces the unpleasant effects of stress. When compared to Semax, it has fewer negative side effects as well.

Both N-acetyl Selank and Semax are potent cognitive enhancers that have shown promise in improving memory, focus, attention, and neurogenesis.

Semax is much more effective in boosting cognition and alleviating depression.

N-acetyl Selank, on the other hand, offers better results when used to treat anxiety.

How to Safely Buy N Acetyl Selank online

If you want to purchase N-Acetyl Selank, then you can find it at most online nootropic retailers.

Price may vary depending on the retailer and the number of doses that come with each package (bottles/sprays).

As always, make sure to do your research before buying any new supplement or drug!

If you're looking for a US-based retailer that sells Selank, you can buy it here:

Are There Any N-Acetyl Selank Alternatives?

Since N-Acetyl Selank is a more potent and bioavailable version of Selank, there are no direct alternatives with as strong benefits.

However, you can stack N-Acetyl Selank with various other supplements to get the most out of it (like a choline source).

For example, one popular combination is using N-Acetyl Selank with Alpha GPC for enhanced focus and attention.

For people who experience side effects while taking N-Acetyl Selank, it's often recommended to stick with regular Selank or another cognitive enhancer that's not quite as strong.

There are also some synthetic nootropics, like Phenylpiracetam or Noopept, which have similar benefits to N-Acetyl Selank without any of the potential side effects.

These supplements can be used if you're looking for something a bit stronger than regular Selank.


What is N-Acetyl Selank amidate used for?

N-Acetyl Selank amidate can be utilized as a broad-spectrum therapeutic in the treatment of the metabolic syndrome.

Often used for anxiety, immune strengthening, stomach protection, weight control/metabolic syndrome prevention, and opioid and alcohol withdrawal/addiction treatment.

What is N-Acetyl Selank amidate?

The Russian drug N-Acetyl Selank amidate is a nootropic and anxiolytic peptide developed by the Institute of Molecular Genetics of the Russian Academy of Sciences.

Does N-Acetyl Selank amidate help sleep?

It is a sedative with nootropic/anti-anxiety effects, meaning it helps to calm your mind. It's wonderful when used in conjunction with anti-depressant pills or alone. It improves brain inflammation. It promotes deep, peaceful sleep.

Can I stack N-Acetyl Selank amidate and Semax?

People that want to enhance mental clarity, memory, and focus may indeed benefit from the Selank/Semax combination that produces strong anti-anxiety effects. It has applications in the treatment of anxiety and depression.

Can I put my N-Acetyl Selank amidate in the refrigerator?

Yes and it should be kept in the refrigerator at temperatures below 35 degrees Fahrenheit after reconstitution.