Emoxypine Succinate is used as an Anxiolytic and is similar to pyridoxine which is Vitamin B6. Studies show that Emoxypine is effective in normalizing the sleep-wake cycle and promoting enhanced cognitive function with low side effects.
So recently I came across a rather interesting Nootropic called; Emoxypine Succinate, or Mexidol, on Reddit. Let's take a closer look at it, shall we?
Here's what we will be covering today:
- What is Emoxypine Succinate?
- How does it work?
- What are the benefits and side effects?
- How much should you take?
- What other Reddit users are saying about Emoxypine
So without further ado, let's just jump straight into it.
What Is Emoxypine Succinate?
Emoxypine is an Anxiolytic when used as the succinate salt.
It has a similar structure as pyridoxine which is a type of Vitamin B6.
Emoxypine was first synthesized in Russia by a company called, PharmaSoft.
Though it isn't approved for any particular medical use in the EU and the US, it is widely used in Russia.
According to this study, we can see that it shows promising results as an Anxiolytic.
Scientists observed an antidepressant effect as well as neuroprotective and anti-inflammatory action.
Other studies suggest that Emoxypine may improve blood circulation in the brain as well as being cardioprotective.
What is the half-life for Emoxypine?
When taken orally (the succinate salt form) it has a rapid onset and short half-life at around 3 hours.
Because it's a slow-release drug, it may have a longer half-life in the body than with some of the other more fast-acting nootropics.
How Does It Work?
There is a general consensus that Emoxypine's mechanism of action is believed to be its antioxidant and neuroprotective abilities.
The information we have about Emoxypine is very limited.
This is what I could find:
- Emoxypine inhibits free radicals and increases antioxidant enzymes (helps with learning and memory processes)
- It blocks the formation of leukotrienes
- It modulates/enhances GABA and acetylcholine receptors in the brain
- Helps with metabolism and blood supply (blood cells) as well as membrane structures (structural and functional organization)
- Helps with receptor complexes (has membrane protective effects)
- Impacts lipid-protein ratio
It has also been shown to improve cognitive function in patients with Alzheimer's disease.
What Are The Benefits & Side Effects?
As briefly mentioned above Emoxypine seems to be very effective when it comes to certain types of conditions.
These conditions are:
- Restores behavioral disorders
- Acute alcohol intoxication
- Neurodegenerative diseases
Since it inhibits free radicals in the brain it would make sense why it is seen as neuroprotective.
In the studies I linked to previously we can also see how effective it was on the participants, normalizing their behavior following stressful events.
"The most pronounced anxiolytic action was observed upon the administration of emoxypine."
It also seems to have Anti-inflammatory effects by blocking leukotrienes from forming.
This study demonstrates the efficiency and how it diminishes the magnitude of a systemic response.
What's The Right Dosage?
From what I could find on Reddit people take anywhere from 50mg to 2grams.
2 grams seems to be pretty over the top if you ask me. I always recommend taking a smaller dose in the beginning and then gradually working your way up.
The Succinate Powder comes in 10 and 30 grams. As for the capsules, you can get 60 or 120pills. One pill is 125mg.
As a rule of thumb, I always start out with the lowest dose possible which in this case is 125mg (1 capsule).
As I alluded to earlier, Emoxypine has been known to help with membrane-bound enzymes.
These are proteins that act as catalysts for biochemical reactions in cells.
They recognize the substrate and bring them to the "active site".
Their structure determines their function which is why membrane-bound enzymes are very important for cellular processes.
There are 3 kinds of enzymes:
- Integral Proteins (they're attached to the membrane)
- Peripheral proteins (attached to integral proteins)
- Transmembrane Proteins (connected with the lipid bilayer)
Blood Cells & ATP Production: Metabolism and Blood Supply
Adenosine Triphosphate (ATP) is the main molecule that powers biochemical reactions in cells.
It also plays a role within erythrocytes.
Red blood cells are responsible for transporting oxygen throughout arteries and veins of the body.
Emoxypine helps with the production of ATP which is crucial for all organisms including plants.
This is because ATP powers metabolic reactions that occur throughout the body.
When it comes to cellular processes, the more efficient a cell's metabolism - the more active it will be and live longer.
A quick example: a cell that is not metabolically active will die without having been given any hormonal stimuli from outside sources.
What is emoxypine good for?
This chemical has purported antistress and anxiety effects. It has been found to improve brain blood circulation by blocking thrombolysis, inhibiting cardiovascular function, lowers high blood cholesterol, vascularity, and anti-aging functions.
What is Mexidol used for?
This is a related drug that is used for the treatment of strokes, brain injuries, and other conditions. It has been shown to improve memory and cognitive function.
Overall, Emoxypine Succinate is a very promising compound with a wide range of benefits.
From anxiety, receptor complexes, free radical oxidation, anti-stress, and restoring behavioral disorders - it has been seen to have a therapeutic effect in many areas.
As for the right dosage, I always recommend starting out with the lowest dose possible, and then gradually working your way up.
The powder comes in 10 and 30 grams and the capsules come in 60 or 120pills. Each pill is 125mg.