Can you take Modafinil everyday?


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Modafinil is a unique, and relatively new type of smart drug. It is one of the most commonly prescribed compounds for the treatment of narcolepsy and excessive daytime sleepiness.

Its stimulant properties however mean that it can be used as a smart drug by healthy individuals in order to boost their cognition and mental abilities to a higher level.

But does taking Modafinil on a daily basis lead to tolerance or addiction? And does it have any long term health effects?

In this article we will attempt to answer these questions.

 

 

Read Also: My Top 3 Favourite Nootropics Of All Time

 

What is Modafinil?

Modafinil (brand name: Provigil) is one of the most popular nootropic agents available worldwide today.

It was developed in France during the late 1970s and has been used since then mostly for medical purposes (e.g as an adjunct treatment for narcolepsy).

However, Modafinil had been off patent since 2003, after which many online pharmacies began selling it as an unregulated nootropic agent.

It is now one of the most widely-used nootropics among today’s college students and young professionals.

As a smart drug, Modafinil can be used to promote wakefulness in individuals who need it without causing the nervousness or irritability that is normally associated with caffeine.

It also has some very interesting cognitive enhancing properties.

It can keep individuals alert for longer periods of time as well as promote faster and more accurate responses to signals and environmental stimuli.

These effects improve an individual’s overall productivity, efficiency, and cognitive performance.

Modafinil has very minimal side effects, which makes it a very attractive choice for many people when compared to other stimulants like amphetamine and cocaine.

 

What’s the best dosage?

Modafinil affects the central nervous system and works mainly by improving the alertness of users.

It almost completely blocks the reuptake of dopamine, norepinephrine, and serotonin in the brain.

As a result, it can cause a large release of these neurotransmitters in the brain, resulting in a feeling of euphoria.

This is why many people get addicted to it pretty quick.

However, at dosages that are safe and effective for medical purposes, Modafinil does not have serious side effects like those caused by prescription stimulants like cocaine (which is more addictive than Modafinil).

People usually take anywhere from 100 to 300 mg of Modafinil early in the Morning (taking it later in the day will result in Insomnia).

 

How Frequently Should You Take It?

Modafinil is an interesting smart drug.

Its chemical structure causes it to have very different effects from other drugs that many people would consider “smart drugs”.

It is not actually a stimulant, because it does not directly affect the dopamine and norepinephrine neurotransmitters in the brain.

However, Modafinil does affect these neurotransmitters in a secondary manner by increasing the amount of glutamate that is made available to the brain (glutamate is a major excitatory neurotransmitter).

In addition, Modafinil has been found to have numerous effects on other neurochemicals including:

  • Glial cell line-derived neurotrophic factor (GDNF)
  • Norepinephrine (norepinephrine is responsible for alertness)
  • Acetylcholine (acetylcholine helps us pay attention)
  • The AMPA receptor (AMPA receptors are needed for synaptic plasticity and memory formation in the brain)
  • Dopamine receptors (dopamine receptors play an important role in learning, mood and pleasure).

The way that Modafinil works is very different from most other smart drugs. Hence, it is difficult to say exactly how often you should take Modafinil in order to get the most out of it.

That being said, it’s generally considered a bad idea to take Modafinil everyday because tolerance will build up quickly (if you use it more than 3-4 times per week).

 

How long does it last?

By increasing the body’s ability to process glutamate, Modafinil helps promote what scientists call “long term potentiation”.

It is believed that this process is one of the primary reasons why people feel more alert and attentive when they use Modafinil.

Long term potentiation basically means that synaptic plasticity (a phenomenon that allows neurons in your brain to grow and connect with one another) increases drastically when using Modafinil.

This is why you don’t crash like you would with caffeine or other stimulants, once the drug wears off.

However, the exact duration that Modafinil lasts depends on many factors such as:

  • Individual factors
  • Bodyweight and metabolism
  • How you take Modafinil (e.g some people feel more alert when they take it on an empty stomach)

According to a scientific review most of Modafinil’s effects are felt for around 7-8 hours after ingestion. This would mean that if you take 200 mg of Modafinil in the morning and experience its full effects for 7-8 hours then there is no need to re-dose with another dose.

However, because all of these factors affect how long Modafinil lasts, it’s not possible to accurately predict how long it will last for everyone.

Modafinil can be detected in your blood stream for up to 2 days after ingestion at dosages that are within safe medical benchmarks (200-400 mg).

 

In Summary

Modafinil is a unique, and relatively new type of smart drug.

It is one of the most commonly prescribed compounds for the treatment of narcolepsy and excessive daytime sleepiness.

Its stimulant properties however mean that it can be used as a smart drug by healthy individuals in order to boost their cognition and mental abilities to a higher level.

Lastly, it is not adviced to take Modafinil daily because it builds up tolerance fast. Most people cycle it on-and-off in a dosage range of 100 to 200 mg.

 

Read Also: My Top 3 Favourite Nootropics Of All Time

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