3 Nootropics To Take With Adderall to Maximize Its Usefulness

Do you take Adderall? If so, do you want to maximize its usefulness without becoming addicted?

Nootropics are safe supplements that can help you think more clearly and focus better. They're designed to work with Adderall in order to prevent addiction.

In this article I'll discuss 3 nootropics I take with my Adderall to maximize its usefulness without becoming addicted.

You don't have to be a college student or professional who needs an extra boost of energy during the day in order for these nootropics to be useful for you!

Anyone who takes Adderall will benefit from taking these nootropics as well because they reduce the risk of addiction while increasing the benefits of using it.

So without further ado, let's get started!

How Does Adderall Work in The Brain?


Adderall is a stimulant prescribed for ADHD.

It has both amphetamines and some off-label uses for treatment of narcolepsy, chronic fatigue syndrome, or executive function disorder.

Adderall works by increasing the activity of norepinephrine/dopamine in the prefrontal cortex of the brain to increase attention span, improve hyperactivity and impulsive behavior.

Its mechanism of action in the brain is very similar to that of Ritalin, just with a greater effect.

Amphetamine, the active ingredient of Adderall, is a compound that is part of the phenethylamine class.

Its effects in the brain are similar to another stimulant, methamphetamine (crystal meth).

Adderall's effects in the brain are similar to that of methamphetamine because amphetamine can be broken down into dextroamphetamine and levoamphetamine.

This breakdown is essential for its effects on dopamine/norepinephrine activity, which I explained above.

It also has some side effects like loss of appetite (which results in weight-loss) and wakefulness, which is why it's used as a treatment for ADHD (and as a Nootropic).##The Dangers Of Adderall Drug Dependence

Since Adderall is an amphetamine, people who take this medication often feel an intense desire to keep taking it in order to experience the pleasurable effects of increased energy and productivity.

Adderall can cause physical dependence, meaning that someone taking this medication will need to keep taking it on a regular basis in order to prevent the reoccurrence of specific withdrawal symptoms.

These withdrawal symptoms can include dizziness, upset stomach, insomnia and headaches.

If you read personal stories from people who have taken Adderall, you will find that many of them describe the mental effects as compared to those associated with cocaine.

If someone takes Adderall for an extended period of time and then stops taking it all at once, they may experience intense cravings for the drug which can lead to Adderall drug abuse.

Nootropics - A Healthy Alternative To Adderall

Nootropics are a safe and healthy alternative to Adderall.

As briefly mentioned above, Adderall is a powerful stimulant with potent side-effects.

Rather than using the drug as a shortcut, those looking for brain power without the negative consequences can try introducing nootropic compounds into their lifestyle instead.

Nootropics are substances which either improve memory, focus, motivation, creativity or even mood without any of the risks associated with prescription medication, such as Adderall.

In the following section I'll go into detail about four nootropics that are effective for this purpose.


Racetams work by increasing the brain's sensitivity to neurotransmitters, which results in better focus and concentration - even with little or nothing else done on your part!

The result is enhanced memory (including working memory), increased mental clarity, better comprehension, and more accurate decision-making abilities.

Popular Racetams include:

  • Aniracetam
  • Piracetam
  • Phenylpiracetam
  • Oxiracetam

Compared to Piracetam (the original racetam), Aniracetam is much stronger - meaning it has a positive effect on mood as well.

Also known for its anti-anxiety benefits, Aniracetam's effects are similar to those of a prescription drug like Xanax - only without the side-effects or addictive properties!


As I've mentioned before, Adderall depletes choline levels. This means that if you don't restore them, your brain will suffer as a result.

If this happens consistently over time it can lead to serious problems, such as "brain fog", memory loss or in my case nasty headaches.

Fortunately, there are a number of excellent choline supplements available to prevent this from happening.

Choline is also known for its positive effects on mood - making it an invaluable tool in the fight against Adderall-induced depression!

"We previously found that choline supplementation increased adult hippocampal neurogenesis, a function compromised by stress, lowered in depression, and boosted by antidepressants; and increased levels of growth factors linked to depression, like brain-derived neurotrophic factor."

Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327365/


Perhaps best known for its ability to decrease anxiety and improve concentration, L-theanine is quickly becoming one of the most well-researched and promising nootropic compounds on the market.

There is also evidence to suggest it can help reduce or even prevent feelings of "Adderall Crash" (fatigue and depression) as well.

Additionally, L-theanine is capable of increasing brain levels of the neurotransmitter Serotonin - which can help to improve mood and promote relaxation!

If you take any of the 3 nootropics listed above with Adderall, you will have a much more positive experience.

Of course, Adderall is still going to be habit-forming so you should still take steps to minimize your use of the drug.

Personally I recommend taking no more than 25mg per day - and even less if possible (I personally only take 5 to 25 mg daily combined with Choline, L-theanine and one of the Racetams.)

This will help you get the most out of Adderall while minimizing its potential for negative side-effects.

Vitamins to Take with Adderall


When you take Adderall, there are a lot of different vitamins you can take to make sure you are maximizing your results.

B-Vitamins are essential for mental function and energy production.

When you take Adderall, it can deplete the B-vitamins in your body which may lead to a crash from taking too much of this medication.

You should make sure that if you do decide to take adderall, that you supplement with a b complex vitamin to prevent the crash.

If you are deficient in these vitamins, it can lead to depression, fatigue and trouble concentrating.

Vitamin B-12 is extremely important for brain function as well as energy levels which will be depleted quickly when taking Adderall due to its effects on stimulating neurotransmitters like dopamine and norepinephrine.

These B vitamins are water-soluble, meaning your body does not store them. You need to replenish these nutrients daily or you can suffer from symptoms of deficiency like fatigue and mental fogginess.

Adderall and Magnesium

Magnesium is another very important mineral that you should supplement with when taking Adderall.

Magnesium is responsible for over 300 different chemical reactions in your body, including neurotransmitter production which will be affected by the medication.

Magnesium also helps protect neurons and supports healthy brain function as well as heart health, strong bones and a healthy immune system.

The perfect dose is usually between 50 to 500 mg.

Vitamin D And Adderall

Vitamin D builds up slowly in the body through diet and sunlight exposure.

It is a fat-soluble vitamin (or hormone) that has many important functions in your central nervous system, cardiovascular system and immune system.

Vitamin D deficiency can lead to depression, stress sensitivity, chronic pain (including headaches), fatigue, muscle weakness or aches/pains associated with fibromyalgia and should be supplemented with if you are deficient.

The perfect dose is usually between 2000 to 5000 IU daily, but it varies depending on how low your levels are. You can get a test from your doctor or order one yourself online to see where your levels are.

If you are deficient, it is best to start with a low dose and work your way up until you reach the perfect level for your body composition and needs.

The safe vitamin D upper limit is 5000 IU daily if taking orally (and this can be taken in one dose or several small doses throughout the day).

Stack L-Tyrosine And Adderall To Enhance The Effect And Aid Recovery

L-tyrosine is an amino acid that is important in the process of making dopamine, epinephrine, norepinephrine and thyroid hormones.

This also helps with memory formation as well as improving your cognitive function through various processes like attention span and focus.

L-tyrosine can be used to treat depression when taken daily at 1000 mg doses over a long period of time.

It is important to take l-tyrosine with other amino acids, especially those that have a high amount of branched chain amino acids which are crucial for cognitive function and energy levels as well as heart health.

When you stack L-tyrosine with Adderall, you are truly increasing your cognitive abilities.

It is best to take l-tyrosine about 60 minutes before you plan on taking Adderall so that it will have time to absorb into your body and reach the brain in high amounts, making it most effective for enhancing the effects of this medication.

Are Nootropics As Good As Adderall?

Different nootropics have different mechanisms of action, therefore some are better than Adderall for some things.

That being said, Nootropics are common alternatives to stimulants like Adderall because these kind of stimulants often lead to addiction.

Nootropics are a great alternative that provide the same effects without any side effects and will not lead to addiction, which is very important for some users who want relief from their symptoms but don't want a dependency on a substance.

They can be taken daily and will not lead to dependency or addiction, unlike many stimulants like Adderall which is often abused for its effects.

What Nootropic Is Most Like Adderall?


If you're looking for a Nootropic that gives you incredible alertness, focus and energy, I would highly recommend Modafinil.

Even though Modafinil is a prescription drug in most countries, it's a wonderful replacement to Adderall, and is generally considered a Nootropic.

It doesn't have any of the nasty side effects that come with Adderall, and you can take it at your discretion!

Modafinil is very similar to Adderall in its function – both will give you incredible amounts of energy and mental acuity.

However, unlike Adderall, Modafinil is not a controlled substance in most countries.

This means it's much easier to get your hands on (no prescription required) and you don't have the fear of getting in trouble for possessing it.

It also doesn't raise blood pressure or give you that jittery feeling like amphetamine-based Adderall does.

Bottom Line

If you are having trouble with Adderall, try taking it in combination with other nootropics and vitamins.

There are 3 main nootropics you can take with Adderall in order to max out its effectiveness (Choline, a Racetam and L-theanine).

Vitamins such as L-tyrosine will help to boost your cognitive abilities and give you energy.

Vitamin D helps with focus and concentration as well as heart health, while Modafinil gives you incredible amounts of mental acuity along with the benefits of Adderall without any side effects or dependency issues.

If I had to pick a favorite, I would recommend stacking L-tyrosine and choline with Adderall to maximize its effects.

FAQ - Nootropics and Adderall

What Are the Benefits of Nootropics When Taken With Adderall?

The benefits are that by taking Nootropics, you are being proactive in taking steps to improve your mental health and overall well-being.

Nootropics can help release dopamine and norepinephrine in a natural way which will lead to an improved mood and reduced depression.

What Are Some of the Side Effects of Taking Nootropics With Adderall?

Side effects for some people may include insomnia, anxiety or jitteriness.

Some nootropics can cause headaches if taken in large doses or on an empty stomach.

Other nootropics may have other side effects which you should research to determine if they are right for your needs.

Most people can take Nootropics with Adderall without experiencing any adverse side-effects, but it is always best to check with a doctor before taking them together just in case.

What Can I Take With Adderall to Increase Its Effectiveness?

You can stack Adderall with a choline source, L-theanine or one of the Racetams to increase the overall effectiveness.

What Can I Take With Adderall to Decrease Its Effectiveness?

The most common thing that decreases the effectiveness of stimulants like Adderall is Acidic juices, which contain citric acid.

Citric Acid will bind to the Adderall and render it useless.

Popular Acidic juices are: orange juice and grapefruit juice.