Sulbutiamine: A Nootropic for Energy, Focus and Mood

Updated May 13, 2024 by | Reviewed by William Gallagher, MNeuroSci
(Estimated reading time: 7 minutes)

Do you ever feel like your brain is on autopilot?

You’re not alone. It turns out that most people are walking around in a mental fog, and it’s affecting their lives more than they realize.

But there’s good news!

Sulbutiamine can help you get back to feeling like yourself again.

This nootropic supplement has been shown to increase energy levels, improve mood and focus, and even boost memory function.

And best of all, it comes with very few side effects compared to other nootropics on the market today.

If you want to feel like yourself again, then read on, as I take a closer look at this incredible nootropic down below.

What is Sulbutiamine and how does it work?

Sulbutiamine (also known as Arcalion) is a synthetic derivative of thiamine, or vitamin B1.

Sulbutiamine was first synthesized in the lab in 1936, and was approved for human consumption by the Japanese Health Ministry back in 1980.

Since then, Sulbutiamine has been used to treat fatigue, memory loss and depression.

It’s also sometimes prescribed as a mood enhancer because it can help improve your overall sense of well-being.

Sulbutiamine works by crossing the blood-brain barrier and then converting into two key neurotransmitters.

These are known as thiamine (vitamin B) and GABA, which is short for gamma aminobutyric acid.

When these chemicals enter your bloodstream, they’re able to cross through the blood–brain barrier, delivering them to your brain.

Once there, they’re able to improve the function of two important neurotransmitters that are largely responsible for regulating mood and energy levels.

When Sulbutiamine is taken as a supplement, it can help restore these chemicals back into your body so you feel like yourself again!

Why should you take Sulbutiamine?

Sulbutiamine is a great supplement for anyone looking to improve their energy levels, mood and focus.

It’s also extremely safe when taken in the right dosages, which I will discuss later on down below.

There are three main reasons why you should consider Sulbutiamine to help you feel like yourself again:

  • It’s very safe to take
  • It can help improve your mood and energy levels
  • It has few side effects compared to other nootropics on the market today

It has been shown in clinical studies to be safe when taken at the right dosages – but it is not recommended to exceed more than 800mg per day.

It also works fast.

It has been shown to work in as little as 30 minutes after taking your first dose!

How much Sulbutiamine should you take?

Most people find that starting off with around 300 milligrams is a good idea when they first start taking Sulbutiamine.

You should take this amount first thing in the morning with a glass of water to test your tolerance levels, and assess how it affects you before going any further.

If you find that 300 milligrams is too much for you (you’ll know because you feel nauseous or uncomfortable), then simply reduce your dosage to around 200 milligrams, and try both of these amounts again over the course of a few days.

Once you’re used to taking Sulbutiamine in this way, then you can start increasing your dose slowly until you reach the optimum amount for yourself.

This usually falls somewhere between 300 – 800 milligrams per day – but it really is different for everyone.

You can also take your dosage with a meal, as this will help to reduce any nausea that you might feel from taking such a high dose of Sulbutiamine.

Sulbutiamine vs. Thiamine: What’s the Difference?

Many people wonder whether they can simply take a thiamine supplement instead of Sulbutiamine.

The truth is, taking Thiamine will never have the same effect as taking Sulbutaimine.

Thiamine is water-soluble and does not cross into your brain to deliver all those important neurotransmitters that are responsible for keeping you energized and focused.

Sulbutiamine is a synthetic version of Thiamine and is fat-soluble, which means it crosses the blood-brain barrier more easily.

It is also much more bioavailable than Thiamine, meaning it is much easier for your body to absorb.

Sulbutiamine also has a positive effect on the GABA neurotransmitter system, whereas Thiamine does not.

In fact, Sulbutaimine works in two ways: by crossing the blood-brain barrier and converting into thiamin (vitamin B) or GABA.

This means Sulbutaimine has a much greater effect on your brain than Thiamine ever could!

Here are some of the key points you need to know about taking Sulbutiamine:

  • It is fat-soluble, so it easily crosses from your digestive system into your bloodstream and then into your brain.
  • It is a synthetic version of Thiamine
  • It works in two ways: firstly, it crosses into your brain to deliver the neurotransmitters; secondly, it converts into thiamin (vitamin B) or GABA.
  • When you take Sulbutaimine as a supplement, it can help improve mood levels rapidly – most people only need 30 minutes!
  • It works fast, and it has few side effects compared to other nootropics on the market today.
  • You should not exceed more than 800mg per day – but you can always start with 300 milligrams first thing in the morning, assess your tolerance levels over a few days, then increase slowly until you find the optimum dose for you.

Possible Benefits of Sulbutiamine

When you take Sulbutiamine as a supplement, you can expect to feel the following benefits:

  • More Energy
  • Improved Mood
  • Focus and Concentration Assistance
  • Less Anxiety or Stress Levels

Again, these effects may vary from person-to-person. Some people will notice one benefit more than another – but all of them are very noticeable when you first start taking Sulbutiamine.

Sulbutaimine Side Effects

Although Sulbutiamine is a safe nootropic to take, you should not exceed more than 800mg per day – and even this may be too much for some people.

If you find that Sulbutaimine is giving you side effects such as nausea or headaches, then simply reduce your dosage until the symptoms go away – it might only take a few days of taking less Sulbutiamine to get used to taking it.

The most commonly reported side effects of Sulbutiamine are:

  • Upset Stomach
  • Dry Mouth
  • Headaches
  • Some people also report that Sulbutiamine gives them a “stimulant-like effect,” making it difficult to sleep. This is normal and should not be cause for concern – but you may want to stop your dose earlier in the day if this does happen.

There are no long-term Sulbutaimine side effects reported – which means you can take this supplement safely for as long as necessary to get all of the benefits.

How does Sulbutiamine feel?

People who take Sulbutiamine report that it makes them feel more alert, awake and focused.

It also helps to improve their overall mood – which is why so many people use this supplement as an anti-depressant or antidepressant agent.

Many people also report that they experience reduced levels of stress and anxiety when taking Sulbutiamine.

The effects of Sulbutiamine are very similar to the stimulant caffeine, which should not be surprising since it also delivers increased energy levels and focus.

When you take Sulbutaimine as a supplement, you will notice the benefits within 30 minutes – but they may last all day long depending on your dosage!

You can take Sulbutiamine in the morning, to help give you a natural boost of energy throughout your day.

Sulbutiamine for Chronic Fatigue

One of the most common reasons people take Sulbutiamine is to help with chronic fatigue.

When you suffer from a lack of energy on a regular basis, it can have an impact on your daily life – and this may lead to feelings of frustration or depression as well.

If you find that caffeine makes you jittery or nervous – or even if you have a caffeine sensitivity – then Sulbutiamine is a great alternative for boosting your energy levels.

Sulbutaimine has been shown to help people who suffer from chronic fatigue, as well as those suffering from asthenia (lack of strength).

If you are looking for an improved mood, more energy and better concentration, then Sulbutiamine is a great choice for you.

It has few side effects compared to other nootropics on the market today – but it may cause mild stomach upset, nausea or headaches if taken at higher doses.

Sulbutaimine can take up to 30 minutes before its full benefits are noticed, but it may last all day.

People who take Sulbutiamine report that they feel more alert and focused after taking the supplement – which makes this an excellent choice for anyone who needs motivation to complete tasks or get through their workday!

Sulbutiamine For Memory

Sulbutiamine is also used for improving memory.

The cholinergic system is responsible for transmitting signals between neurons in your brain – which are critical to helping you remember things.

When taking Sulbutiamine, it may help stimulate this neurotransmitter so that more signals can be transmitted through the nervous system – allowing you to have improved memory function as a result.

It also increases dopamine, which is another important neurotransmitter that helps your brain process information and makes it easier to recall memories based on their emotional associations or experiences with them.

Sulbutiamine For Better Athletic Performance

When it comes to athletic performance, many people turn to stimulants like caffeine and ephedrine.

However, these types of supplements can be dangerous when used for long periods of time – which is why Sulbutiamine may be a better option if you want an energy boost before working out or competing in your favorite sport!

Sulbutiamine is great because it has been found to improve athletic performance without making you feel nervous or jittery.

It also improves blood flow, which may help your muscles recover faster after a tough workout – allowing you to get back into the gym more quickly and achieve better results!

Sulbutiamine for Anxiety

When people take Sulbutiamine, it can help to improve their mood and reduce feelings of stress or anxiety.

It is also used as a nootropic for improving mental performance – which makes this supplement ideal if you are feeling unfocused or struggling with motivation.

As an anti-depressant agent, Sulbutiamine may be taken daily by people who want to improve their mood and motivation.

Where to buy Sulbutiamine

Sulbutiamine is available in tablet, capsule, and powder form.

Each tablet, or capsule, contains 750 mg of sulbutiamine.

It's marketed under the Arcalion, Enerion, Bisibuthiamine, and Youvitan brand names in some countries.

This nootropic is also available on most online vendors. Keep in mind that the FDA has not approved this supplement as a drug to prevent or treat any conditions.