TeaCrine Guide: Everything You Need To Know Before Buying

Updated July 10, 2024 by | Reviewed by William Gallagher, MNeuroSci
(Estimated reading time: 5 minutes)

TeaCrine (Theacrine) is structurally similar to caffeine and found in the kucha leaf. It helps in promoting wakefulness, focus and energy.

If you read yesterday's blog post you'd know that I briefly touched upon theacrine and its effects.

After watching a couple of videos about TeaCrine this morning I figured why not write an article about it going into details with what I didn't cover in yesterday's blog.

So that's exactly what I'm going to do today.

Here are some of the topics I will be covering:

  • What is TeaCrine® (Theacrine)?
  • How does it work?
  • Are there any benefits and/or side effects?
  • Can you stack it with other stimulants?
  • What about the dosage?
  • Where can you buy it?
  • What other people on Reddit are saying about it

.... So without further ado, let's just get right into it!

What Is TeaCrine® (Theacrine)?

As I briefly touched upon in the beginning, theacrine is a naturally occuring purine alkaloid found in the kucha leaf.

It is patented by a company called; Compound Solutions.

In yesterday's blog I wrote about a very similar compound called; Dynamine Methylliberine.

Dynamine Methylliberine is another of their trademarked compounds with similar effects asTeaCrine.

That being said, TeaCrine is a slower, milder compound with a longer duration than caffeine.

People who are taking TeaCrine experience better focus, mood, energy levels and motivation (without the jittery).

TeaCrine works synergistically with caffeine to enhance cognitive and physical performance without building a dependency on the compound.

A study even suggests that whenever supplementing with TeaCrine and caffeine, the bioavailability of TeaCrine is enhanced.

And the potency of it actually increases as well, which is quite fascinating.

According to Compound Solutions TeaCrine is an ideal supplement for anyone looking to increase their energy levels without increasing their heart rate or blood pressure.

It is the perfect non-stimulant compound that delivers powerful energy without the jitters or crash.

How Does It Work?

As briefly mentioned in the beginning, TeaCrine is similar to caffeine. The way TeaCrine works mechanistically is by regulating dopamine as an agonist as well as inhibiting adenosine.

Compared to caffeine, TeaCrine modulates the adenosine receptors which in turn decreases sensitivity. Caffeine however blocks adenosine receptors.

This is why you'll experience a lesser tolerance buildup when using TeaCrine compared to caffeine.

CompoundSolutions are going into details about it in this video:

How Does TeaCrine Compare To Other Similar Stimulants?

If we compare TeaCrine (theacrine) to other stimulants like Dynamine Methylliberine and caffeine, what's unique about TeaCrine is that you'll experience:

  • Less tolerance buildup
  • The duration of the effects are longer
  • No crash and jittery

TeaCrine has a much slower onset and longer duration than both Dynamine Methylliberine and caffeine.

According to CompoundSolution TeaCrine takes anywhere from 3 to 6 hours to hit its peak followed by a steady peak for 3-5 hours.

This is why most people only take TeaCrine early in the morning (it lasts almost the entire day, depending on how much you take).

So if you're looking for a better alternative to Caffeine and Dynamine without all the side effects such as; jittery and crashes then TeaCrine is a great choice.

What About The Safety & Side Effects?

In a randomized, double-blinded crossover pilot trial, the researchers found that a 200mg dose of TeaCrine increased energy levels, reduced the feeling of fatigue and improved concentration in the subjects.

Interesting enough they found no side effects.

Here's what the researchers concluded:

"These preliminary data support the benefits of acute TeaCrine supplementation on subjective “energy” levels and some indices of mental performance."

It's worth noting that the study was 8 weeks of daily supplementation (200mg) and what they found was that it had no impact on ;

  • Blood pressure
  • The heart rate
  • Lipid profiles (cholesterol)
  • Liver, kidney and overall immune function

I have tried looking on various forums and sub-reddits and couldn't find anyone reporting any negative side effects.

According to the anecdotes and the study listed above, it seems to be extremely safe with no side-effects.

What's The Best TeaCrine Dosage?

Any information about TeaCrine when it comes to the right dose you should take is very limited.

That being said, if we follow the same dosages as used in the study I mentioned earlier then an effective dose would look like this:

  • A low dose: 50-100mg
  • A medium dose: 150-200mg
  • A high dose: 250-300mg

In the study they used 200mg. From the various anecdotes I could find people are using anywhere from 200 to 500mg.

500mg seems to be waaay over the top if you ask me. I would highly recommend starting out small and then work your way up.

It usually comes in both powder form and capsules. One capsule is 100mg and should be enough to provide long-lasting and jitter-free energy.

Even though it has a low tolerance buildup, most people take TeaCrine on and off (cycle in and out).

Remember that TeaCrine takes longer to kick in so be patient and careful not to take more than the recommended dose.

Where Can I Buy TeaCrine (Theacrine)?

Since TeaCrine is a legal supplement you can buy it pretty much anywhere on the internet.

I haven't tried it myself so I can't recommend a specific source. That being said I buy my phenibut, dynamine and other favorite nootropics from NootropicsDepot.

I haven't had any bad experiences with the guys over at NootropicsDepot and what I like about them is that they test every batch to ensure high quality and purity.

The only downside I have experienced buying from them is the delivery time which varies alot.

I live in Europe and it usually takes anywhere from 8 to 13 business days before I receive my package. So keep that in mind if you are in a hurry.

I haven't explored the different shipping methods on their website but I'm sure that if you're willing to pay extra for faster shipping, you can probably find a faster shipping method at checkout.

You can find TeaCrine on NootropicsDepot here.

What People On Reddit Say About TeaCrine (Theacrine)


The first thread on Reddit that I could find is from a user called; u/Disturbed83.

Disturbed83 is sharing his own 8 weeks experience with TeaCrine.

He starts off by saying that he has already gone through 2 bottles (1gram). The effects he experiences on/off are pronounced.

One thing that he notices is how there is no crash after discontinueing (he states that he feels less inclined to consume coffee the days after).

Disturbed83 is consuming 180-200mg of TeaCrine from NootropicsDepot which seems to be the sweet spot for him.

He finds that the anti-inflammatory and pain killing effects are real. He also briefly mentions that he has experienced an increase desire to exercise.

He then finishes off the thread by saying that he takes it first in the morning due to the long half-life (it can be difficult to fall asleep).

Another thread I found on Reddit is from a user called; u/JakeandOreos.

JakeandOreos starts off by saying that Theacrine has saved him from depression.

He then goes on to say that although Theacrine isn't perfect it lifts him out just enough to see some hope. He then states the following:

"Let me tell you, this stuff works..."

JakeAndOreos goes into details about him being depressed (winter time and a terrible breakup).

He takes 200mg and can feel the immediate effect it has on his mood or as he puts it:

"I feel the weight lifting off my shoulders."

JakeAndOreos then finishes off by saying that his hopelessness is almost completely gone.

In Conclusion

TeaCrine (Theacrine) is a natural and legal supplement similar to caffeine.

It is found in the kucha leaf and helps in promoting wakefulness, focus and energy.

TeaCrine is safe to take with low side effects and studies show that it has zero effects on the cardiovascular system.

It has similar benefits to caffeine but without the jitter and crash.

Lastly, an effective dose of TeaCrine is anywhere from 100 to 200mg/daily consumed in either powder form or capsules.