Cognizin Citicoline Guide: Everything You Need To Know

Written on May 20, 2023 by | Reviewed by William Gallagher, MNeuroSci

Cognizin Citicoline is a popular Nootropic that supports mental energy, focus and attention.

Hey guys!

In today's article we're going to take a closer look at a popular Nootropic called; Cognizin Citicoline.

Here are some of the topics we will be covering:

  • What is Cognizin Citicoline?
  • What are the side effects of citicoline?
  • Does it increase dopamine?
  • What are other people on Reddit saying about it?

.... So without further ado, let's just get straight into it.

What is Cognizin Citicoline?

Citicoline is a brain energizer linked to multiple cognition enhancing and neuro-regenerative effects, including support for focus, better attention and overall brain health. Recently, it's being used by biohackers as a Nootropic.

From a brain support standpoint, Cognizin Citicoline optimizes brain cells, mitochondria for healthy energy metabolism. It raises brain levels of neuro building phosphatidylcholine and supports the brain chemicals; acetylcholine, dopamine, and norepinephrine.

Cognizin Citicoline helps synthesize and repair brain cell membranes, and protects brain cells from the damaging effects of free radicals and aging.

Let's talk about Citicoline its Nootropic affects.

Citicoline is well known to energize the brain cells for peak cognitive performance and without the crash that is often associated with other stimulants (such as caffeine etc.)

It's an enhancer of mental focus, attention, and supports overall brain health and cognitive function. It may even help to improve mild age-related memory issues.

How does it work?

Cognizin Citicoline is a single nootropic that boosts multiple pathways to optimize mental performance and whole brain health.

Human research has linked it to improvements in mental energy memory, attention, reaction time, concentration, and focus.

I have found 3 studies about Cognizin Citicoline here that shows:

  1. How it Increases motor speed and attention in healthy adolescent males
  2. How it increases Brain Energy (ATP) by 14% and Speeds up Formation of Brain Membranes by 26%
  3. How citicoline improves memory performance

Let's take a look at how Cognizin Citicoline may help with brain health and mental performance.

From a brain energy perspective, Citicoline helps the brain generate electrical impulses by supporting proper function of mitochondria.

In one of the study I linked to above, they found that Cognizin Citicoline increased frontal lobe brain energy by up to 14%.

Citicoline has also been shown to stimulate phosphor, lipid synthesis and turnover, reflecting brain renewal and leading researchers to suggest Cognizin Citicoline may help to reverse certain age related changes to the brain.

As we can see from the 2nd study I linked to above, it suggests that Cognizin stimulates new brain cell formation by as much as 26% (it helps to form acetylcholine, which is associated with memory learning and mental processing).

Acetycholine declines with age and low acetylcholine is linked to brain degeneration.

What are the side effects of Citicoline?

From the studies I could find most of them confirm its safety.

That being said, there are in some rare instances where Citicoline is shown to cause mild digestive and nerve issues in the subjects.

Overall Citicoline is relatively safe with a low side effect profile.

What are the benefits & side effects?

As I have already mentioned in the beginning, the benefits experienced when taking Citicoline could be due to its effect on the brain function.

Citicoline plays an important role in mitigating the effects of memory loss.

Studies show that Citicoline helps people improve learning and enhances their attention span.

This is why people use it as a Nootropic. It leads to better focus and concentration.

From one of the study I linked to previously, it showed that Citicoline improves overall neuronal activity which in turn leads to a reduction in neuronal death.

So to summarize the benefits people are experincing using Citicoline, here's a list:

  • Enhanched mood - an overall sense of well-being
  • Better memory and more focused (not distracted by small things)
  • Steady, and sustainable, levels of mental energy without the crash

Does Citicoline increase Dopamine?

The short answer is; Yes it does.

Citicoline increases norepinephrine as well as dopamine in the brain.

It has also been shown to increase serotonin and acetylcholine.

I found a study here that shows the efficacy of Citicoline and how, mechanistically, it increases dopamine levels in the brain.

What's the right dosage?

When it comes to the right dose it usually depends on your goals and tolerance. Based on one of the study I linked to previously we can see the following:

  • A High Dose of Citicoline is: 500 mg/daily for 14 days
  • A Lose Dose of Citicoline is: 250 mg/daily for 14 days

I also found some anecdotes from Reddit where people take micro dosages (50-100 mg) and stack with other Nootropics such as

... And other racetams for an enhanced cognitive effect.

As is the case with most Nootropics I always recommend starting out with a low dose and then gradually work your way up to asses the potential negative effects it may have on you.

Cognizin Citicoline comes in both powder form and capsules.

1 capsule is 250 mg and can be split into 2 dosages (125mg twice a day) when first starting out.

What Are People On Reddit Saying About Cognizin Citicoline?


The first thread I could find on Reddit is by a user called; Grizzled_Johnson.

He starts off by stating that he restored his dopamine system in just 2 days using Citicoline.

Grizzled_Johnson then goes on to say how he started watching porn from an early age (daily PMO) and how these quick dopamine rushes have depleted him.

You can read the entire thead here (it's an interesting read)

The second thread I could find is by a user called; u/arramire.

He starts off by asking if Cognizin Citicoline can negatively effect onces sleep.

He then goes on to say that he just recently started taking Citicoline in his stack and how he is experiencing trouble when it comes to falling asleep at night.

You can read the entire thread right here.

Where can I buy it?

Citicoline can be bought on most Nootropic websites.

That being said, I only have experience buying from NootropicsDepot. I haven't tried their Citicoline yet, but I get my Phenibut and Triacetyluridine from them and they are always high quality.

What I like about them, and the reason why I only buy from them, is that they lab test every single batch.

That way you know that the quality and purity of the batch is tested before you take it.

Their Cognizin Citicoline Powder comes in both 30gr and 60gr. You can find it here.

They also have 250mg capsules that come in 60ct and 180ct bottles. You can find them here.

The only downside I have experienced buying from NootropicsDepot is the delivery time.

I live in Europe and it usually takes anywhere from 8 to 13 business days for my package to arrive.

So keep that in mind if you're in a hurry.

I'm sure you can find a quicker shipping method at checkout if you're willing to pay extra upfront.

In Conclusion

Cognizin Citicoline is a brain energizer that supports mental energy, focus and attention.

It has been shown to have low side effects as well as a relatively high safety profile.

Citicoline is shown to increase dopamine levels in the brain which is why people are reporting an overall sense of well-being when taking it.

A safe dose is generally considered to be in the 100-250mg range.

It comes in both powder and capsule form and can be bought on most Nootropic websites.